Leonardo went to Milan c.1482 and remained at the court of Ludovico Sforza for 16 years. In this time he composed the greater part of his Trattato della pittura and the extensive notebooks that demonstrate the marvelous versatility and penetration of his genius. As court artist he also organized elaborate festivals. Severe plagues in 1484 and 1485 drew his attention to problems of town planning, an interest which was revived during his last years in France. Many drawings …showed first 75 words of 654 total…

…showed last 75 words of 654 total… physical world, he continued his scientific investigations, concerning himself with problems of geology, botany, hydraulics, and mechanics. In 1510-11 his interest in anatomy quickened considerably. At the same time he was active as painter and sculptor, had many pupils, and profoundly influenced the Milanese painters. A painting generally ascribed to this period is the St. Anne, Mary, and the Child (Louvre), a work that exemplifies Leonardo's handling of sfumato misty, subtle transitions in tone