Chse 235<Tab/> Efosa Asemota Drug report #2<Tab/> Cytotec/ Misoprosto Therapeutic category Mucosal Protective gent<Tab/> Use/ indicator For the treatment and prevention of NSAID-induced gastroduodenal ulcers. Also indicated for the treatment of duodenal ulcers caused by Peptic Ulcer Disease (PUD). Adverse reaction The most frequent gastrointestinal adverse events were diarrhea (10.7%), abdominal pain (7.3%), nausea (4.2%), flatulence (3.3%), and dyspepsia (3.2%). The incidence of diarrhea was 7.8% when the …showed first 75 words of 246 total…

…showed last 75 words of 246 total…The recommended adult oral dosage for the prevention and treatment of NSAID-induced gastroduodenal ulcer is 400 to 800 µg a day in divided doses. NSAIDs should be taken according to the schedule prescribed by the physician. When appropriate, misoprostol and NSAIDs are to be taken simultaneously. Misoprostol should be taken after food. Reference:www.drugs.com, www.pharmclips.com, http://www.rxmed.com,http://www.rxmed.com/b.main/b2.pharmaceutical/b2.prescribe.html